How Knot to Confuse Proteins: Using Bondles to Catalog Bonded Linear Segments, Tong Gao '24

Abstract: Proteins are folded linear molecular chains that are responsible for most cellular functions. Their 3D structures, including intra-molecular interactions, contain crucial information about their dynamics, functions, and evolution. Extending traditional concepts and frameworks of knot theory, we will discuss the algebraic structure of bondles and how they distinguish the topologies of proteins.