Professor Dharni Vasudevan, Bowdoin College
"Pharmaceutical Interactions at the Solid-water Interface: Implications for Predicting Contaminant Fate"
Several antibiotics of concern possess cationic and anionic groups and, therefore, occur as anions (e.g., cephalosporins), cations (e.g. azithromycin), or zwitterions (e.g., fluoroquinolones) at environmentally relevant pH values. Ionic compounds possess unique driving forces for sorption to solid phases: cationic amine groups, and potentially anionic carboxylic and hydroxyl groups allow for interaction via cation exchange, surface complexation and cation bridging, if the appropriate receptor sites are available on the surface. This works explores how the knowledge of these interaction mechanisms can be leveraged to build predictive models for pharmaceutical sorption to soils and design appropriate passive sampling devices.
Friday, November 3, 2017 at 1:10pm
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